An Ademco panel would be the way to go, they also give you the option of having wireless addressable smokes on most panels, which will save a bunch of labor if it is a large house. If one goes off the keypad can display what head went off with a description. The wireless is also supervised so if one head drops offline for whatever reason the panel will go into trouble, it will also provide a low battery warning at the keypad. The only down side is that batteries only seem to go dead between 1 and 3 in the morning...