I agree that the ‘S’ type fuses would effectively eliminate over-fused circuits.

One advantage of CB’s is the flexibility in constructing a breaker panel. Would you have a “snap-in” fuse holder similar to a CB such that circuits could be added by installing the appropriate fuse-holder in a panel’s empty slot? I suppose that if there were no such thing as a “half-size fuse holder”, that would tend to limit panel overcrowding.

With fuses as the primary OCP, how would you handle GFCI and/or Arc Fault protection?

While single-phasing may be a motor-related problem, what about 2-pole common trip OCP for 240vac appliances (ex. dryer)?