Not directly above panel- I say no.

Working space extends to ceiling. That's not so easy to call. I would consider the "ceiling" to be the bottom flange of the I-joists. Even so, the copper lines attached directly to the flanges I would consider at worst a 'de minimus' (too small to matter) violation.
The drain line is another matter. On balance, I'd let it slide as well. The plumber has little flexibility as to where the drain must run, and there is plenty of room to open the panel. I say this assuming that the vertical part of the drain does not also intrude on working space from the side!