Clem, if you have home runs long enough for voltage drop to be a real concern, you should look into using sub-panels. This increases the performance of the system, as well as possibly even reducing labor and materials costs.
We're wiring a 7500+ sq.ft. house, and we used a pair of sub-panels, one for each main panel. This is because we used the two 200-amp panels to divide the standby-generator loads from the non-generator loads; and only needed one 200-amp ATS.
