Panda Platinum Internet Security will stop 98% of malware and spyware which are the new threats. I believe everyone is pretty much overcome the attachment vulnerabilities.
http://www.pandasoftware.com/home/default.asp If you are interested in an operating system that will allow zero penetrations of any kind whatsoever, and never needs updating then I suggest Bodacion Technologies "Hydra" System. It requires no updates or much IT support, to speak of. It's impenetrable. This would be an operating system that you would offer a customer with the base system starting at around $17,000.
http://www.bodacion.com/products.html http://mail-index.netbsd.org/port-pdp10/2003/04/15/0000.html I do not work or represent either of these companies.
I do use their products though.