I still may be an old machine with no PS2 jack. This would be real evident if it has no USB jacks. If it has USB jacks with no PS2 (Common with late models)If it is truly a old machine with no PS2 jack, only a serial jack, a adapter will work you will have to use a driver for it (the mouse) as most serial stuff is not P&P. Might find some web site with mouse drivers, or may be able to go into the bios and point it to the serial port to make the mouse work. Robert