The International Residential Code, section R502.8.2 forbids such acts:
"Cuts, notches and holes bored in trusses, laminated veneer lumber, glue-laminated members or I-joists are not permitted unless the effects of such penetrations are specifically considered in the design of the lumber."
To me this would mean engineering approval. Many I-joists have K-Os in the approved areas. All engineered lumber comes with literature that should be consulted when cuts are considered.
