One more very important piece of infomation is needed, the load profile. Published loss data is usually only provided at 100% loading so the actual loading is important.

Core loss is present 100% of the time a transformer is energized. Conductor loss is only present when the transformer is loaded. This loss varies with the square of the loading, at 90% load there will only be 81% of the full load conductor losses.

So if your transformer is fully loaded 24hx7d (like a production line) you would want a design that minimizes conductor losses. But if your transformer was only loaded 80% for 16hx5d and 30% for 8hx5d + 24hx2d (like an office building) you might want a design that minimizes core losses.