As a general rule, I agree with iwire, common sense.
Now I thought that I had read that you can run a max of 600' underground between manhole/handhole, but I am starting to think that is a local PoCo regulation, bacuase I can't find it again in the NEC...
The only other limitation I can think besides conductor damage is the pulling method. If you have a 240' fishtape in a 250' run...
I try not to rely on breaking the run at a coupling to pull in a rope of string, it's just not fun! Easier (I think) to set a box as you run the conduit.