Only Theoretical:

Lets assume you have a step down transformer feeding a subpanel. No continuous neutral between primary side and secondary side of transformer.

You must bond the neutral on the secondary side of your transformer to the equipment case. I understand that this is to keep all of your voltages relative to the same ground voltage throughout the building.

But, what if you didn't bond the neutral? So what if your air conditioning units operating at 480V and your computers operating at 120V were at really strange voltages relative to each other?

The only danger I see if if somebody was holding on to two live neutrals on different systems at the same time. But that's probably not a good idea anyway. I'm sure there's a down side but I can't see what it is. Two of us at work have been discussing this and I knew somebody where would know the answer.